Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846135 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL31301878 | 0.77 | CA2 (0.40) | CA2EPHX2CXCL8KDM4ELMNA | |
| SCHEMBL18778812 | 0.76 | LDHA (0.42) | CA2EPHX2CXCL8KDM4ECXCR1 | |
| SCHEMBL92834 | 0.76 | — | — | |
| SCHEMBL14178232 | 0.76 | CA2 (0.38) | CA2EPHX2CXCL8KDM4EALDH1A1 | |
| SCHEMBL3713808 | 0.76 | — | — | |
| SCHEMBL1161702 | 0.75 | EPHX2 (0.38) | CA2EPHX2CXCL8PLA2G10NR4A2 | |
| SCHEMBL28356260 | 0.75 | ALOX15 (0.39) | CXCL8LMNAALOX15CYP2C19HSD17B10 | |
| SCHEMBL1751607 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5379762 | 0.74 | MEN1 (0.39) | CA2EPHX2CXCL8KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154944-B1 | SUBSTITUTED PYRIDINONES AS MGAT2 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-14 | — | — | EP | disclosed |