SCHEMBL19956445

SCHEMBL19956445

COc1cc(-c2cc(-c3cc(C)cc(OC)c3OP(Oc3ccc(C(C)(C)C)cc3C(C)(C)C)Oc3ccc(C(C)(C)C)cc3C(C)(C)C)c(OC)cc2OC)c(O)c(C(C)(C)C)c1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
NR1I2 O75469 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20129539 0.80 CA1 (0.37) CA1CA2ALDH1A1GAANR1I2
SCHEMBL18523535 0.78 CA2 (0.53) CA1CA2ALDH1A1GAA
SCHEMBL18523532 0.73 CA2 (0.49) CA1CA2ALDH1A1GAA
SCHEMBL17277942 0.71 APEX1 (0.34) CA1CA2ALDH1A1GAANR1I2
SCHEMBL11056664 0.71 TSHR (0.37) CA1CA2ALDH1A1
SCHEMBL16996689 0.71 CA2 (0.67) CA1CA2ALDH1A1GAA
SCHEMBL29683430 0.70 ALDH1A1 (0.34) CA1CA2ALDH1A1GAA
SCHEMBL18191801 0.69 MAPT (0.33) CA1CA2ALDH1A1
SCHEMBL16014947 0.69 CA2 (0.46) CA1CA2ALDH1A1
SCHEMBL20133515 0.69 NR1I2 (0.32) ALDH1A1GAANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3293189-A1 PHOSPHITES WITH A DIHYDROXYTERPHENYL AND TWO PHENOLS Evonik Degussa GmbH (DE) 2018-03-14 EP disclosed