⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19957100 | 0.83 | ALDH1A1 (0.33) | — | |
| SCHEMBL19957251 | 0.78 | — | — | |
| SCHEMBL23825290 | 0.71 | MMP1 (0.39) | — | |
| SCHEMBL23825418 | 0.71 | MMP1 (0.39) | — | |
| SCHEMBL23825415 | 0.71 | MMP1 (0.39) | — | |
| SCHEMBL23825292 | 0.71 | MMP1 (0.39) | — | |
| SCHEMBL16844295 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL22575223 | 0.69 | MMP1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL22575224 | 0.69 | MMP1 (0.34) | — | |
| SCHEMBL23157811 | 0.68 | ZDHHC20 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188778-A1 | NOVEL POLYMORPHS OF 4-[3-CHLORO-4-(N'-CYCLOPROPYL UREIDO)PHENOXY]-7-METHOXYQUINOLINE-6-CARBOXAMIDE, ITS SALTS AND PROCESS FOR THE PREPARATION THEREOF | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2021-06-24 | — | — | US | disclosed |
| EP-3293177-A1 | TYROSINE KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-14 | — | — | EP | disclosed |