SCHEMBL19959433

SCHEMBL19959433

O=C(O)CCOCCOCCOCCCOCCOCCOCCOCCOc1ccc(Br)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.51
FFAR1 O14842 3/20 0.51
FFAR4 Q5NUL3 1/20 0.51
PLA2G4B P0C869 3/20 0.49
KDM4E B2RXH2 1/20 0.49
RARB P10826 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
PPARA Q07869 2/20 0.45
MMP2 P08253 1/20 0.45
PPARD Q03181 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12224519 0.95 L3MBTL1 (0.56) L3MBTL1FFAR1FFAR4PLA2G4BKDM4E
SCHEMBL12224513 0.95 L3MBTL1 (0.56) L3MBTL1FFAR1FFAR4PLA2G4BKDM4E
SCHEMBL1822418 0.86 L3MBTL1 (0.67) L3MBTL1FFAR1FFAR4MEN1KMT2A
SCHEMBL1822003 0.84 FFAR1 (0.58) L3MBTL1FFAR1FFAR4PLA2G4BMEN1
SCHEMBL17732030 0.83 KDM4E (0.52) L3MBTL1FFAR1FFAR4KDM4EMEN1
SCHEMBL19489958 0.81 PPARA (0.61) L3MBTL1FFAR1FFAR4PLA2G4BKDM4E
SCHEMBL8355954 0.81 PPARA (0.61) L3MBTL1FFAR1FFAR4PLA2G4BKDM4E
SCHEMBL28543148 0.81 PPARA (0.61) L3MBTL1FFAR1FFAR4PLA2G4BKDM4E
SCHEMBL12223524 0.81 PKM (0.56) L3MBTL1FFAR1PPARA
SCHEMBL5638782 0.81 PKM (0.56) L3MBTL1FFAR1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180074067-A1 Novel Reagents for Directed Biomarker Signal Amplification SIRIGEN GROUP LIMITED (GB) 2018-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180074067-A1 Novel Reagents for Directed Biomarker Signal Amplification RNGTT, CAPG, CD2BP2 L3MBTL1 3469/4885FFAR1 3921/4885FFAR4 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.