Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990322 | 0.98 | SNCA (0.50) | SNCAHSD17B1HSD17B2MAPK13GCGR | |
| SCHEMBL2778388 | 0.88 | SNCA (0.61) | SNCAKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL12581415 | 0.83 | HSD17B1 (0.63) | SNCAHSD17B1HSD17B2KDM4ENPC1 | |
| SCHEMBL12562851 | 0.80 | HSD17B1 (0.61) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12562796 | 0.80 | HSD17B1 (0.61) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL1987764 | 0.80 | SNCA (0.50) | SNCAHSD17B1HSD17B2MAPK13GCGR | |
| SCHEMBL12562798 | 0.78 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12562792 | 0.78 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL12562788 | 0.78 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A | |
| SCHEMBL9933404 | 0.78 | HSD17B1 (0.59) | HSD17B1HSD17B2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554107-B | AZAADAMANTANE DERIVATIVES AND METHODS OF USE | 艾伯维巴哈马有限公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20110152541-A1 | INDUCING LAYER MATERIALS FOR WEAK EPITAXIAL FILMS OF NON-PLANAR METAL PHTHALOCYANINE | SHANGHAI CASAIL DISPLAY TECHNOLOGY LTD. (CN) | 2011-06-23 | — | — | US | disclosed |
| CN-101955491-A | Induced layer material for weak epitaxial growth thin film of non-planar metal phthalocyanin | SHANGHAI ZHONGKE LIANHE DISPLAY TECHNOLOGY CO LTD | 2011-01-26 | — | — | CN | disclosed |
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | DENOVAMED INC. (CA) | 2010-06-03 | — | — | US | disclosed |
| WO-2008128321-A1 | THERAPEUTIC PRO-ANTIBIOTIC AGENTS AND METHODS OF USE THEREOF | DENOVAMED INC. (CA) | 2008-10-30 | — | — | WO | disclosed |
| EP-1909775-A2 | FORMULATION OF RADIOPROTECTIVE ALPHA, BETA UNSATURATED ARYL SULFONES | Onconova Therapeutics, Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016201-A2 | FORMULATION OF RADIOPROTECTIVE α, β UNSATURATED ARYL SULFONES | ONCONOVA THERAPEUTICS, INC. (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | NAT1, NAPEPLD, NR1I2 | SNCA 3311/4885HSD17B1 480/4885HSD17B2 607/4885 |
| US-20110152541-A1 | INDUCING LAYER MATERIALS FOR WEAK EPITAXIAL FILMS OF NON-PLANAR METAL PHTHALOCYANINE | CDYL, PAX3, PAXBP1 | SNCA 3557/4885HSD17B1 2793/4885HSD17B2 2870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.