SCHEMBL1996035

SCHEMBL1996035

CCCC(=O)Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.44
CTNNB1 P35222 1/20 0.44
CES2 O00748 1/20 0.41
ALDH1A1 P00352 3/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
RXRA P19793 2/20 0.39
RXRB P28702 2/20 0.39
RXRG P48443 2/20 0.39
ALOX15 P16050 1/20 0.39
LMNA P02545 2/20 0.38
NOTUM Q6P988 1/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SCN9A Q15858 3/20 0.37
PDGFRB P09619 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998642 0.90 KMT2A (0.41) CES2KMT2AKDM4ERXRARXRB
SCHEMBL2191360 0.86 ESR1 (0.44) CES2ALDH1A1KMT2AKDM4ERXRA
SCHEMBL1995788 0.84 FAAH (0.53) ALDH1A1KDM4ELMNAMAPTL3MBTL1
SCHEMBL1045008 0.83 BCL9 (0.55) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL12758761 0.83 CES2 (0.41) CES2ALDH1A1KMT2AKDM4ERXRA
SCHEMBL15765770 0.82 CES2 (0.47) CES2KDM4EGAARXRARXRB
SCHEMBL29009999 0.82 SCN9A (0.40) KMT2AKDM4ERXRARXRBRXRG
SCHEMBL13228832 0.81 BCL9 (0.55) BCL9CTNNB1ALDH1A1KMT2AKDM4E
SCHEMBL29000619 0.79 CES2 (0.44) CES2ALDH1A1KMT2AKDM4EGAA
SCHEMBL21164057 0.78 SCN9A (0.45) CES2ALDH1A1RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
US-5840725-A Substituted oximes, hydrazones and olefins as neurokinin antagonists SCHERING CORPORATION (US) 1998-11-24 US disclosed
US-5696267-A ANTIHISTAMINES; ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS SCHERING CORPORATION (US) 1997-12-09 US disclosed