SCHEMBL1998642

SCHEMBL1998642

CCCCC(=O)Oc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
RECQL P46063 1/20 0.41
FAAH O00519 2/20 0.41
PSEN1 P49768 4/20 0.39
ALOX5 P09917 3/20 0.39
PPARG P37231 2/20 0.39
CES2 O00748 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
PSEN2 P49810 2/20 0.37
APH1B Q8WW43 2/20 0.37
NCSTN Q92542 2/20 0.37
APH1A Q96BI3 2/20 0.37
PSENEN Q9NZ42 2/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
RXRA P19793 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29009999 0.91 SCN9A (0.40) KMT2AKDM4EMEN1RECQLFAAH
SCHEMBL1996035 0.90 BCL9 (0.44) KMT2AKDM4EFAAHCES2MAPT
SCHEMBL1997128 0.85 FAAH (0.57) KMT2AKDM4EMEN1FAAHALOX5
SCHEMBL1999397 0.84 KIF11 (0.49) KMT2AKDM4EMEN1RECQLPSEN1
SCHEMBL2191360 0.83 ESR1 (0.44) KMT2AKDM4EMEN1RECQLCES2
SCHEMBL12758761 0.80 CES2 (0.41) KMT2AKDM4ECES2TP53MAPT
SCHEMBL904337 0.80 ALDH1A1 (0.33) KDM4EFAAHRXRARXRBRXRG
SCHEMBL15765770 0.79 CES2 (0.47) KDM4ECES2MAPTRXRARXRB
SCHEMBL1194378 0.79 CNR2 (0.41) KMT2AMEN1FAAHPSEN1CES2
SCHEMBL31346764 0.78 KMT2A (0.56) KMT2AMEN1FAAHSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed