Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960694 | 0.91 | GRM7 (0.54) | GRM7TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19960507 | 0.83 | GRM7 (0.58) | GRM7TSHRGAALMNAALDH1A1 | |
| SCHEMBL19953650 | 0.82 | GRM7 (0.57) | GRM7TSHRGAALMNAALDH1A1 | |
| SCHEMBL19960690 | 0.82 | GRM7 (0.57) | GRM7TSHRGAALMNAALDH1A1 | |
| SCHEMBL19960687 | 0.82 | GRM7 (0.55) | GRM7TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19953654 | 0.79 | GRM7 (0.62) | GRM7TSHRGAAALDH1A1MAPT | |
| SCHEMBL19953513 | 0.79 | GRM7 (0.62) | GRM7TSHRGAAALDH1A1MAPT | |
| SCHEMBL19960878 | 0.78 | GRM7 (0.60) | GRM7GAALMNAXIAP | |
| SCHEMBL19960417 | 0.78 | GRM7 (0.66) | GRM7GAALMNAOPRM1 | |
| SCHEMBL19960841 | 0.77 | GRM7 (0.49) | GRM7LMNABIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |