Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960690 | 1.00 | GRM7 (0.57) | GRM7F2TSHRMAPTGAA | |
| SCHEMBL19960865 | 0.93 | GRM7 (0.51) | GRM7F2TSHRMAPTGAA | |
| SCHEMBL19960866 | 0.93 | GRM7 (0.51) | GRM7F2TSHRMAPTGAA | |
| SCHEMBL19960507 | 0.88 | GRM7 (0.58) | GRM7TSHRMAPTGAALMNA | |
| SCHEMBL19960687 | 0.85 | GRM7 (0.55) | GRM7F2TSHRMAPTGAA | |
| SCHEMBL19960694 | 0.84 | GRM7 (0.54) | GRM7TSHRMAPTGAALMNA | |
| SCHEMBL19953513 | 0.84 | GRM7 (0.62) | GRM7TSHRMAPTGAATP53 | |
| SCHEMBL19953654 | 0.84 | GRM7 (0.62) | GRM7TSHRMAPTGAATP53 | |
| SCHEMBL19960696 | 0.82 | GRM7 (0.55) | GRM7TSHRMAPTGAALMNA | |
| SCHEMBL19960417 | 0.80 | GRM7 (0.66) | GRM7GAALMNAHDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |