Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953654 | 1.00 | GRM7 (0.62) | GRM7MAPTGAATSHRMTNR1A | |
| SCHEMBL19953497 | 0.92 | GRM7 (0.55) | GRM7MAPTGAATSHRTP53 | |
| SCHEMBL19953664 | 0.86 | HRH3 (0.46) | GRM7MAPTGAATSHRMTNR1A | |
| SCHEMBL19953510 | 0.86 | HRH3 (0.46) | GRM7MAPTGAATSHRMTNR1A | |
| SCHEMBL19960507 | 0.84 | GRM7 (0.58) | GRM7MAPTGAATSHRTP53 | |
| SCHEMBL19960417 | 0.84 | GRM7 (0.66) | GRM7GAAMTNR1AMTNR1B | |
| SCHEMBL19960690 | 0.84 | GRM7 (0.57) | GRM7MAPTGAATSHRTP53 | |
| SCHEMBL19953650 | 0.84 | GRM7 (0.57) | GRM7MAPTGAATSHRTP53 | |
| SCHEMBL19953501 | 0.81 | GRM7 (0.61) | GRM7 | |
| SCHEMBL19953496 | 0.81 | GRM7 (0.61) | GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |