Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 4/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960823 | 0.77 | ALDH1A1 (0.61) | FABP5ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL19960511 | 0.77 | ALDH1A1 (0.61) | FABP5ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL19960824 | 0.77 | ALDH1A1 (0.61) | FABP5ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL19960593 | 0.75 | FABP5 (0.43) | FABP5ALDH1A1MAPTNPC1LMNA | |
| SCHEMBL19960632 | 0.73 | EGFR (0.43) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL19960649 | 0.70 | EGFR (0.39) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL19960861 | 0.69 | FABP5 (0.42) | FABP5ALDH1A1MAPTGRM7MTNR1A | |
| SCHEMBL19960870 | 0.68 | HRH3 (0.38) | FABP5MAPTGRM7MTNR1AMTNR1B | |
| SCHEMBL10957521 | 0.67 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EIDO1 | |
| SCHEMBL19960879 | 0.66 | MEN1 (0.42) | FABP5MAPTNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |