Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960511 | 0.76 | ALDH1A1 (0.61) | FABP5GRM7MAPTALDH1A1MTNR1A | |
| SCHEMBL19960824 | 0.76 | ALDH1A1 (0.61) | FABP5GRM7MAPTALDH1A1MTNR1A | |
| SCHEMBL19960823 | 0.76 | ALDH1A1 (0.61) | FABP5GRM7MAPTALDH1A1MTNR1A | |
| SCHEMBL19960702 | 0.75 | FABP5 (0.41) | FABP5GRM7MAPTALDH1A1MTNR1A | |
| SCHEMBL19960879 | 0.75 | MEN1 (0.42) | FABP5GRM7MAPTL3MBTL1MTNR1A | |
| SCHEMBL19960814 | 0.71 | MAPT (0.43) | MAPTALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL6220534 | 0.69 | BRPF1 (0.52) | MAPTALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL19960861 | 0.68 | FABP5 (0.42) | FABP5GRM7MAPTALDH1A1MTNR1A | |
| SCHEMBL19953525 | 0.66 | ALDH1A1 (0.44) | FABP5GRM7ALDH1A1NPC1LMNA | |
| SCHEMBL1029693 | 0.65 | MTNR1A (0.77) | GRM7MAPTMTNR1AMTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |