Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960601 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL1689404 | 0.75 | HDAC3 (0.62) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL5536500 | 0.74 | L3MBTL1 (0.61) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL30022965 | 0.73 | RXFP1 (0.69) | ALDH1A1L3MBTL1RAB9ATP53MPO | |
| SCHEMBL505220 | 0.73 | RXFP1 (0.69) | ALDH1A1L3MBTL1RAB9ATP53MPO | |
| SCHEMBL2633385 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL1901172 | 0.72 | ALDH1A1 (0.76) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL28017040 | 0.71 | L3MBTL1 (0.61) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL9761962 | 0.71 | L3MBTL1 (0.61) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A | |
| SCHEMBL12655113 | 0.70 | POLB (0.57) | ALDH1A1HSD17B10CYP1A2L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048928-A1 | CHEMICAL PROBES OF LYSYL OXIDASE-LIKE 2 AND USES THEREOF | PHARMAKEA, INC. (US) | 2018-03-15 | — | — | WO | disclosed |