Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.44 |
| ▸ | HTR6 | P50406 | 12/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960459 | 0.77 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL19953514 | 0.76 | OPRM1 (0.43) | OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL19953535 | 0.70 | OPRM1 (0.39) | OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL4859756 | 0.64 | NPY5R (0.55) | NOTUM | |
| SCHEMBL14685832 | 0.63 | NPY5R (0.50) | — | |
| SCHEMBL2554375 | 0.63 | OPRM1 (0.69) | OPRM1OPRK1OPRL1 | |
| SCHEMBL5556488 | 0.61 | NPY5R (0.49) | — | |
| SCHEMBL19953584 | 0.61 | FABP5 (0.43) | HTR6 | |
| SCHEMBL19953489 | 0.61 | FABP5 (0.43) | HTR6 | |
| SCHEMBL19953533 | 0.61 | FABP5 (0.43) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |