Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19960839 | 0.84 | HDAC4 (0.39) | KCNQ2 | |
| Hydrochloric Acid SCHEMBL19953504 | 0.83 | HDAC4 (0.38) | KCNQ2 | |
| SCHEMBL19953514 | 0.83 | OPRM1 (0.43) | OPRM1OPRK1OPRL1NOTUMKCNQ2 | |
| SCHEMBL19960459 | 0.74 | OPRM1 (0.50) | OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL19953634 | 0.74 | AADAT (0.37) | — | |
| SCHEMBL19960690 | 0.70 | GRM7 (0.57) | OPRM1 | |
| SCHEMBL19953650 | 0.70 | GRM7 (0.57) | OPRM1 | |
| SCHEMBL19960876 | 0.70 | OPRM1 (0.44) | OPRM1OPRK1OPRL1NOTUM | |
| SCHEMBL2467842 | 0.69 | MTNR1A (0.46) | — | |
| SCHEMBL19797799 | 0.69 | MTNR1A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |