Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 6/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.35 |
| ▸ | PER2 | O15055 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944789 | 0.79 | PDE4A (0.36) | KDM4ERECQLMAPTSMARCA4MEN1 | |
| SCHEMBL9844706 | 0.79 | KDM4E (0.60) | PABPC1KDM4ERECQLMAPTTP53 | |
| SCHEMBL19960979 | 0.76 | HTR2A (0.38) | KDM4ERECQLMAPTSMARCA4PBRM1 | |
| SCHEMBL18202181 | 0.76 | PABPC1 (0.49) | PABPC1KDM4ERECQLMAPTTP53 | |
| SCHEMBL18202213 | 0.76 | PABPC1 (0.49) | PABPC1KDM4ERECQLMAPTTP53 | |
| SCHEMBL19960987 | 0.71 | HTR2A (0.42) | KDM4ERECQLMAPTPER2HTR2A | |
| SCHEMBL19960981 | 0.70 | HTR2A (0.41) | KDM4EMAPTPER2HTR2AHTR2C | |
| SCHEMBL10725922 | 0.70 | KDM4E (0.54) | PABPC1KDM4ERECQLMAPTTP53 | |
| SCHEMBL9657474 | 0.70 | KDM4E (0.46) | PABPC1KDM4ERECQLMAPTSMARCA4 | |
| SCHEMBL18202193 | 0.69 | PABPC1 (0.40) | PABPC1KDM4ERECQLMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072704-A1 | Fused-Ring Or Tricyclic Aryl Pyrimidine Compound Used As Kinase Inhibitor | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072704-A1 | Fused-Ring Or Tricyclic Aryl Pyrimidine Compound Used As Kinase Inhibitor | EGFR, ERBB2, ERBB4 | PABPC1 3709/4885KDM4E 3193/4885RECQL 3466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.