Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16201678 | 0.75 | PABPC1 (0.46) | RXFP1PABPC1EIF4HPRNPKMT2A | |
| SCHEMBL18202181 | 0.73 | PABPC1 (0.49) | KDM4EALDH1A1PABPC1RECQLMAPT | |
| SCHEMBL18202213 | 0.73 | PABPC1 (0.49) | KDM4EALDH1A1PABPC1RECQLL3MBTL1 | |
| SCHEMBL9844706 | 0.73 | KDM4E (0.60) | KDM4EPABPC1RECQLMAPTSMARCA4 | |
| SCHEMBL19960975 | 0.70 | PABPC1 (0.45) | KDM4EALDH1A1PABPC1KMT2AMEN1 | |
| SCHEMBL10725922 | 0.65 | KDM4E (0.54) | KDM4EALDH1A1PABPC1RECQLL3MBTL1 | |
| SCHEMBL16201684 | 0.65 | CDK5 (0.45) | KDM4EALDH1A1PABPC1KMT2AMEN1 | |
| SCHEMBL18202193 | 0.64 | PABPC1 (0.40) | KDM4EALDH1A1PABPC1KMT2ARECQL | |
| SCHEMBL10742255 | 0.63 | RXFP1 (0.58) | KDM4ERXFP1ALDH1A1PABPC1PTGDR2 | |
| SCHEMBL6981939 | 0.63 | PIM1 (0.42) | KDM4EALDH1A1PABPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128364-A | Antiasthmatic, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1992-07-07 | — | — | US | disclosed |