Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19967687 | 1.00 | PKM (0.38) | PKMADAM17MAPK1ALDH1A1MEN1 | |
| SCHEMBL19961311 | 0.79 | POLB (0.46) | PKMALDH1A1POLBNPC1RAB9A | |
| SCHEMBL19967733 | 0.79 | POLB (0.46) | PKMALDH1A1POLBNPC1RAB9A | |
| SCHEMBL19961336 | 0.77 | BCHE (0.49) | PKMADAM17ALDH1A1MEN1KMT2A | |
| SCHEMBL19961348 | 0.76 | PKM (0.35) | PKMADAM17MAPK1ALDH1A1MEN1 | |
| SCHEMBL27924756 | 0.74 | PKM (0.52) | PKMADAM17MAPK1ALDH1A1MEN1 | |
| SCHEMBL2038319 | 0.74 | PKM (0.49) | PKMADAM17MAPK1ALDH1A1MEN1 | |
| SCHEMBL2041019 | 0.73 | PKM (0.46) | PKMADAM17MAPK1ALDH1A1MEN1 | |
| SCHEMBL2042725 | 0.72 | PKM (0.50) | PKMADAM17MAPK1ALDH1A1MEN1 | |
| SCHEMBL30067 | 0.71 | PKM (0.47) | PKMADAM17MAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072666-A1 | ENOYL REDUCTASE INHIBITORS WITH ANTIBACTERIAL ACTIVITY | NOVALEX THERAPEUTICS INC (US) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072666-A1 | ENOYL REDUCTASE INHIBITORS WITH ANTIBACTERIAL ACTIVITY | FAR1, TECR, ECI1 | PKM 3369/4885ADAM17 2429/4885MAPK1 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.