Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153394 | 0.84 | L3MBTL1 (0.40) | ALDH1A1SMN1; SMN2KDM4EMAPTMAOB | |
| SCHEMBL23153395 | 0.75 | L3MBTL1 (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL19962831 | 0.75 | POLB (0.36) | ALDH1A1SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL19962798 | 0.74 | MEN1 (0.40) | ALDH1A1SMN1; SMN2HTTLMNAKDM4E | |
| SCHEMBL23130699 | 0.71 | MEN1 (0.33) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL23130687 | 0.68 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2HTTLMNAKDM4E | |
| SCHEMBL6030738 | 0.67 | POLB (0.76) | ALDH1A1SMN1; SMN2HTTLMNAMITF | |
| SCHEMBL29417999 | 0.67 | POLB (0.76) | ALDH1A1SMN1; SMN2HTTLMNAMITF | |
| SCHEMBL4006392 | 0.64 | HPGD (0.69) | ALDH1A1SMN1; SMN2HTTLMNAMITF | |
| SCHEMBL7081917 | 0.64 | NPC1 (0.61) | ALDH1A1SMN1; SMN2HTTLMNAMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| WO-2018048879-A1 | METAL CHELATORS FOR IMAGING, THERAPEUTICS, AND BIOANALYSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | TBCA, SLC39A3, TBL3 | ALDH1A1 3272/4885SMN1; SMN2 3559/4885HTT 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.