Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517905 | 0.77 | KDM4E (0.44) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL15161179 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10285329 | 0.74 | ALDH1A1 (0.41) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL23153394 | 0.74 | L3MBTL1 (0.40) | KDM4EALDH1A1MAPTGAACA12 | |
| SCHEMBL2358278 | 0.73 | NQO2 (0.61) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12519128 | 0.73 | KDM4E (0.59) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL17897095 | 0.73 | MEN1 (0.52) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12517908 | 0.73 | KDM4E (0.38) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL23723240 | 0.72 | ALDH1A1 (0.60) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL17897171 | 0.72 | MEN1 (0.51) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-03-30 | — | — | US | disclosed |
| WO-2018048879-A1 | METAL CHELATORS FOR IMAGING, THERAPEUTICS, AND BIOANALYSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961197-B2 | Metal chelators for imaging, therapeutics, and bioanalysis | TBCA, SLC39A3, TBL3 | MEN1 324/4885KMT2A 3881/4885KDM4E 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.