Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR1E | P28566 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.40 |
| ▸ | ITGAL | P20701 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951587 | 0.89 | ITGB2 (0.51) | ITGB2ICAM1ITGALALOX5SLC6A5 | |
| SCHEMBL30374580 | 0.88 | ITGB2 (0.40) | HRH3ITGB2ICAM1ITGALSLC6A5 | |
| SCHEMBL4535076 | 0.86 | HTR1D (0.48) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL29222912 | 0.78 | ITGB2 (0.46) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL19963571 | 0.77 | ATM (0.52) | — | |
| SCHEMBL5808674 | 0.76 | HTR1D (0.51) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL13912170 | 0.76 | HRH3 (0.47) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL7598348 | 0.76 | ITGB2 (0.55) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL18814494 | 0.76 | REN (0.49) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL1486141 | 0.76 | REN (0.49) | HTR1DHTR2CHTR1EHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510041-B1 | PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-31 | — | — | EP | disclosed |
| WO-2018048698-A1 | PROCESSES FOR SEPARATING AGGREGATED PROTEINS FROM MONOMERIC PROTEINS IN A BIOLOGICAL SOLUTION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-15 | — | — | WO | disclosed |