Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR1E | P28566 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.46 |
| ▸ | ITGAL | P20701 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29222912 | 0.90 | ITGB2 (0.46) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL19963538 | 0.86 | HTR1D (0.42) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL24106906 | 0.85 | ITGB2 (0.57) | ITGB2ICAM1ITGALSLC6A5CYP3A4 | |
| SCHEMBL4536009 | 0.85 | ITGB2 (0.57) | ITGB2ICAM1ITGALSLC6A5CYP3A4 | |
| Hydrochloric Acid SCHEMBL28591529 | 0.84 | ITGB2 (0.56) | ITGB2ICAM1ITGALSLC6A5CYP3A4 | |
| SCHEMBL5808674 | 0.84 | HTR1D (0.51) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL7598348 | 0.84 | ITGB2 (0.55) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL24106817 | 0.82 | ALOX5 (0.48) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL28614792 | 0.82 | ALOX5 (0.48) | HTR1DHTR2CHTR1EHTR2BHTR2A | |
| SCHEMBL13912236 | 0.82 | HTR1D (0.49) | HTR1DHTR2CHTR1EHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106872435-B | Protein bio luminescence imaging sensor based on acid imide multiarm polymers | 重庆大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-106872435-A | The protein bio luminescence imaging sensor of Ji Yu perylene diimide multiarm polymers | 重庆大学 | 2017-06-20 | — | — | CN | disclosed |
| EP-1982716-B1 | NOVEL HISTIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-8236844-B2 | Histidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-8236844-B2 | Histidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-8236844-B2 | Histidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20090149658-A1 | Novel Histidine Derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090149658-A1 | Novel Histidine Derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090149658-A1 | Novel Histidine Derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-1982716-A1 | NOVEL HISTIDINE DERIVATIVE | Nippon Zoki Pharmaceutical Co. Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149658-A1 | Novel Histidine Derivatives | HRH4, HNMT, HRH3 | HTR1D 89/4885HTR2C 125/4885HTR1E 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.