Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | SORD | Q00796 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965244 | 0.82 | ROCK1 (0.32) | ROCK1 | |
| SCHEMBL7236541 | 0.74 | TRPV1 (0.44) | RPS6KA5TRPV1SORD | |
| SCHEMBL27992493 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL19965020 | 0.74 | CDK4 (0.36) | — | |
| SCHEMBL19965170 | 0.73 | KDM4E (0.39) | — | |
| SCHEMBL19965160 | 0.68 | CYP1A2 (0.41) | — | |
| SCHEMBL28477218 | 0.68 | RPS6KA5 (0.38) | RPS6KA5TRPV1ROCK1 | |
| SCHEMBL19155132 | 0.67 | NPC1 (0.38) | — | |
| SCHEMBL29406937 | 0.67 | NPC1 (0.38) | — | |
| SCHEMBL23191146 | 0.66 | RPS6KA5 (0.36) | RPS6KA5TRPV1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049324-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | NUMERATE, INC. (US) | 2018-03-15 | — | — | WO | disclosed |