Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | SORD | Q00796 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13028399 | 0.78 | TRPV1 (0.47) | TRPV1ADRA1DADRA1AADRA1B | |
| SCHEMBL16637778 | 0.78 | ROCK2 (0.53) | TRPV1 | |
| SCHEMBL27805031 | 0.76 | SORD (0.66) | TRPV1SORD | |
| SCHEMBL1427479 | 0.76 | TRPV1 (0.51) | TRPV1SORD | |
| SCHEMBL29519276 | 0.76 | TRPV1 (0.51) | TRPV1SORD | |
| SCHEMBL3949154 | 0.76 | TRPV1 (0.51) | TRPV1SORD | |
| SCHEMBL29997962 | 0.75 | HRH4 (0.65) | TRPV1SORD | |
| SCHEMBL2190955 | 0.75 | HRH4 (0.65) | TRPV1SORD | |
| SCHEMBL19965019 | 0.74 | RPS6KA5 (0.38) | TRPV1RPS6KA5SORD | |
| SCHEMBL28477218 | 0.74 | RPS6KA5 (0.38) | TRPV1RPS6KA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | Valo Health, LLC | 2023-06-15 | — | — | US | disclosed |
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | Valo Health, LLC | 2023-06-15 | — | — | US | disclosed |
| US-11548886-B2 | Monocyclic compounds useful as GPR120 modulators | VALO HEALTH, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20210101896-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | Valo Health, LLC | 2021-04-08 | — | — | US | disclosed |
| US-10800773-B2 | Monocyclic compounds useful as GPR120 modulators | INTEGRAL HEALTH, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-20190202821-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | Valo Health, LLC | 2019-07-04 | — | — | US | disclosed |
| WO-2018049324-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | NUMERATE, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
| US-20030055263-A1 | Carboxylic acid derivatives, medicaments comprising these compounds, their use and processes for their production | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548886-B2 | Monocyclic compounds useful as GPR120 modulators | GPR119, GPR180, GPR65 | TRPV1 142/4885GRIN2D 762/4885GRIN3B 315/4885 |
| US-10800773-B2 | Monocyclic compounds useful as GPR120 modulators | GPR119, GPR180, GPR65 | TRPV1 142/4885GRIN2D 762/4885GRIN3B 315/4885 |
| US-20210101896-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | TRPV1 142/4885GRIN2D 762/4885GRIN3B 315/4885 |
| US-20190202821-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | TRPV1 142/4885GRIN2D 762/4885GRIN3B 315/4885 |
| US-20030055263-A1 | Carboxylic acid derivatives, medicaments comprising these compounds, their use and processes for their production | TERT, POT1, REV1 | TRPV1 2572/4885GRIN2D 3586/4885GRIN3B 3701/4885 |
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | TRPV1 142/4885GRIN2D 762/4885GRIN3B 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.