Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.40 |
| ▸ | CBLB | Q13191 | 2/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | UGCG | Q16739 | 4/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19965112 | 0.75 | FFAR4 (0.36) | CBLBMAP3K5CDK5UGCGCDK5R1 | |
| SCHEMBL31069542 | 0.69 | CBLB (0.43) | GRM1CBLBMAP3K5CDK5PIM1 | |
| SCHEMBL9979662 | 0.68 | NPC1 (0.59) | GRM1CBLBCDK5PIM1CSNK1A1 | |
| SCHEMBL10086535 | 0.68 | CBLB (0.52) | GRM1CBLBUGCG | |
| SCHEMBL23703872 | 0.68 | GRM1 (0.46) | GRM1CBLB | |
| SCHEMBL29993525 | 0.68 | GRM1 (0.46) | GRM1CBLB | |
| SCHEMBL1333882 | 0.67 | PIM1 (0.46) | GRM1CBLBCDK5PIM1CSNK1A1 | |
| SCHEMBL14846877 | 0.66 | IDH1 (0.48) | TRPV1PIM1MAP4K1 | |
| SCHEMBL22204175 | 0.66 | NPC1 (0.49) | GRM1MAP3K5ROCK1 | |
| SCHEMBL21211920 | 0.66 | PIM1 (0.44) | GRM1CBLBCDK5PIM1CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | Valo Health, LLC | 2023-06-15 | — | — | US | disclosed |
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | Valo Health, LLC | 2023-06-15 | — | — | US | disclosed |
| WO-2018049324-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | NUMERATE, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183231-A1 | MONOCYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | TRPV1 142/4885GRM1 57/4885CBLB 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.