Sugi Predict

Sugi Predict / Compounds / SCHEMBL1996543

SCHEMBL1996543

SCHEMBL1996543

CCCC1c2ccccc2-c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 6/20 0.54
▸ ACHE P22303 2/20 0.47
▸ BCHE P06276 1/20 0.47
▸ GPR3 P46089 1/20 0.43
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ HRH1 P35367 4/20 0.40
▸ CHRM2 P08172 2/20 0.40
▸ CHRM1 P11229 2/20 0.40
▸ SLC6A2 P23975 2/20 0.40
▸ ADRA1A P35348 2/20 0.40
▸ DRD3 P35462 2/20 0.40
▸ SLC6A3 Q01959 2/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ DRD2 P14416 1/20 0.40
▸ ADRA2B P18089 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313685 0.88 ACHE (0.55) HTR2AACHEBCHEGPR3CA1
SCHEMBL877438 0.86 HTR2A (0.56) HTR2AACHEBCHE
SCHEMBL5353138 0.85 HTR2A (0.64) HTR2AACHEBCHEGPR3CA1
SCHEMBL1449246 0.85 HTR2A (0.54) HTR2AACHEBCHE
SCHEMBL407781 0.85 HTR2A (0.54) HTR2AACHEBCHE
SCHEMBL6061696 0.85 HTR2A (0.54) HTR2AACHEBCHE
SCHEMBL6060761 0.85 HTR2A (0.54) HTR2AACHEBCHE
SCHEMBL6060915 0.85 HTR2A (0.54) HTR2AACHEBCHE
SCHEMBL6060938 0.85 HTR2A (0.54) HTR2AACHEBCHE
SCHEMBL6060774 0.85 HTR2A (0.54) HTR2AACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269401-B Polymer containing piperidine tertiary amine group, anion exchange polymer, and preparation method and application thereof 惠州市亿纬新能源研究院 2023-12-05 — — CN claimed
CN-111269401-A Polymer containing piperidine tertiary amine group, anion exchange polymer, and preparation methods and applications thereof 惠州市亿纬新能源研究院 2020-06-12 — — CN claimed
CN-111269401-B Polymer containing piperidine tertiary amine group, anion exchange polymer, and preparation method and application thereof 惠州市亿纬新能源研究院 2023-12-05 — — CN disclosed
EP-4257196-A1 DISCOVERY OF YEATS2 YEATS DOMAIN INHIBITORS AS NOVEL ANTI-CANCER AGENTS The University of Hong Kong (HK) 2023-10-11 — — EP disclosed
CN-111269401-A Polymer containing piperidine tertiary amine group, anion exchange polymer, and preparation methods and applications thereof 惠州市亿纬新能源研究院 2020-06-12 — — CN disclosed
US-8969624-B2 Cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions EVONIK DEGUSSA GMBH (DE) 2015-03-03 — — US disclosed
EP-2057174-B1 NEW CYCLOPENTADIENYL, INDENYL OR FLUORENYL SUBSTITUTED PHOSPHINE COMPOUNDS AND THEIR USE IN CATALYTIC REACTIONS EVONIK DEGUSSA GMBH (DE) 2014-12-17 — — EP disclosed
US-20140058101-A1 New Cyclopentadienyl, Indenyl or Fluorenyl Substituted Phosphine Compounds and Their Use in Catalytic Reactions EVONIK DEGUSSA GMBH (DE) 2014-02-27 — — US disclosed
US-8618328-B2 Cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions EVONIK DEGUSSA GMBH (DE) 2013-12-31 — — US disclosed
CN-101622264-B Cyclopentadienyl, indenyl or fluorenyl substituted phosphine compounds and their use in catalytic reactions EVONIK DEGUSSA GMBH 2013-09-18 — — CN disclosed
US-8319213-B2 Aryl-aryl dendrimers ISIS INNOVATION LIMITED (GB) 2012-11-27 — — US disclosed
US-20030027017-A1 Light emitter for a display HULL, UNIVERSITY OF (GB) 2003-02-06 — — US disclosed
US-20030021913-A1 Liquid crystal alignment layer CENTRAL RESEARCH LABORATORIES LIMITED (GB) 2003-01-30 — — US disclosed
US-20030018097-A1 Light emitting polymer HULL, UNIVERSITY OF (GB) 2003-01-23 — — US disclosed
WO-2002067343-A1 ARYL-ARYL DENDRIMERS ISIS INNOVATION LIMITED (GB) 2002-08-29 — — WO disclosed
EP-1180765-A1 Optical recording medium and porphycene compound Mitsui Chemicals, Inc. (JP) 2002-02-20 — — EP disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 — — US disclosed
US-6106999-A SENSITIVITY TO GENERAL-PURPOSE VISIBLE LIGHT LASER, SO THAT HIGH-SPEED SCANNING EXPOSURE IS POSSIBLE BY LASER, AND EXTREMELY FINE HIGH RESOLUTION CAN BE OBTAINED; CAN BE USED FOR COATING OR PRINTING UNDER SAFELIGHT IRRADIATING CONDITIONS MITSUI CHEMICALS (JP) 2000-08-22 — — US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 — — EP disclosed
CN-1147522-A Bridged bis-fluorenyl metallocenes, process for preparation thereof and use thereof in catalysts for polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 1997-04-16 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140058101-A1 New Cyclopentadienyl, Indenyl or Fluorenyl Substituted Phosphine Compounds and Their Use in Catalytic Reactions CPS1, CYCS, PFAS HTR2A 3917/4885ACHE 2917/4885BCHE 1468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.