Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15723779 | 0.81 | ALDH1A1 (0.31) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL15491702 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL13605202 | 0.72 | ESR1 (0.31) | — | |
| SCHEMBL15492957 | 0.71 | L3MBTL1 (0.40) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL4781697 | 0.66 | HTT (0.35) | ALDH1A1KMT2A | |
| SCHEMBL19965862 | 0.66 | KDM4E (0.41) | — | |
| SCHEMBL6090787 | 0.62 | BCHE (0.31) | — | |
| SCHEMBL18467791 | 0.62 | PTGS1 (0.31) | ALDH1A1KMT2A | |
| SCHEMBL25930929 | 0.60 | — | — | |
| SCHEMBL24185802 | 0.60 | TMEM97 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10342781-B2 | Diazole amides | CHEMOCENTRYX, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180071257-A1 | DIAZOLE AMIDES | CHEMOCENTRYX, INC. | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071257-A1 | DIAZOLE AMIDES | CCR1, CCRL2, CCR4 | ALDH1A1 919/4885KMT2A 4027/4885L3MBTL1 614/4885 |
| US-10342781-B2 | Diazole amides | CCR1, CCRL2, CCR4 | ALDH1A1 919/4885KMT2A 4027/4885L3MBTL1 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.