Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19967009 | 0.87 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL8260610 | 0.81 | MAPT (0.58) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL19967012 | 0.80 | LMNA (0.41) | MAPTKMT2ATSHRCYP2C19KDM4E | |
| SCHEMBL25609417 | 0.75 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL5520122 | 0.73 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL27629749 | 0.73 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL741956 | 0.71 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18914421 | 0.71 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL17282166 | 0.70 | MAPT (0.50) | MAPTALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL5701048 | 0.70 | ALDH1A1 (0.55) | MAPTALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045907-A1 | NOVEL 2-ACYLAMINOTHIAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-03-15 | — | — | WO | disclosed |