Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433535 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL28976959 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL8140909 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL21233640 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL27272041 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2GAAMAPT | |
| SCHEMBL4102073 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL29679125 | 0.82 | KMT2A (0.47) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL26891587 | 0.81 | WNT1 (0.42) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5701008 | 0.81 | HSD17B10 (0.46) | KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL25281461 | 0.81 | HTR4 (0.39) | ALDH1A1MEN1KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565585-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | Bristol-Myers Squibb Company (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024030968-A1 | COMPOUNDS FOR MODULATING RET PROTEIN | BRYSTOL-MYERS SQUIBB COMPANY (US) | 2024-02-08 | — | — | WO | disclosed |
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |