Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.40 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19967182 | 0.90 | FFAR1 (0.64) | FFAR1FFAR4HRH3 | |
| SCHEMBL19967332 | 0.82 | FFAR4 (0.64) | FFAR1FFAR4HRH3 | |
| SCHEMBL19967045 | 0.78 | FFAR4 (0.49) | FFAR1FFAR4 | |
| SCHEMBL19967142 | 0.76 | FFAR4 (0.64) | FFAR1FFAR4 | |
| SCHEMBL19967149 | 0.75 | FFAR4 (0.61) | FFAR1FFAR4HRH3 | |
| SCHEMBL21168484 | 0.75 | FFAR4 (0.75) | FFAR1FFAR4 | |
| SCHEMBL19967157 | 0.74 | FFAR4 (0.74) | FFAR1FFAR4HRH3 | |
| SCHEMBL19967192 | 0.72 | FFAR4 (0.58) | FFAR1FFAR4HRH3 | |
| SCHEMBL21124269 | 0.72 | FFAR1 (0.47) | FFAR1FFAR4GPR132IKBKB | |
| SCHEMBL19967156 | 0.72 | FFAR4 (0.49) | FFAR1FFAR4MAPK1MAPTGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3509588-B1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | INTEGRAL HEALTH INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20210347768-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | VALO HEALTH, INC. | 2021-11-11 | — | — | US | disclosed |
| US-10865201-B2 | Bicyclic compounds useful as GPR120 modulators | VALO HEALTH, INC. (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190218208-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | VALO HEALTH, INC. | 2019-07-18 | — | — | US | disclosed |
| WO-2018049328-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | NUMERATE, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865201-B2 | Bicyclic compounds useful as GPR120 modulators | GPR119, GPR180, GPR65 | FFAR1 20/4885SNRNP200 4283/4885FFAR4 38/4885 |
| US-20190218208-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | FFAR1 20/4885SNRNP200 4283/4885FFAR4 38/4885 |
| US-20210347768-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | FFAR1 20/4885SNRNP200 4283/4885FFAR4 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.