Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19967337 | 0.85 | TDP1 (0.42) | TDP1MAPTGAASMN1; SMN2ROCK1 | |
| SCHEMBL19967340 | 0.82 | FFAR1 (0.49) | TDP1MAPTMDM2KMT2ACTDSP1 | |
| SCHEMBL19967065 | 0.80 | FFAR4 (0.50) | SMN1; SMN2HRH3 | |
| SCHEMBL19967185 | 0.79 | TDP1 (0.46) | TDP1MAPTMDM2KMT2ACTDSP1 | |
| SCHEMBL19967098 | 0.78 | TDP1 (0.45) | TDP1MAPTMDM2KMT2ACTDSP1 | |
| SCHEMBL21168479 | 0.77 | TDP1 (0.46) | TDP1MAPTMDM2KMT2ACTDSP1 | |
| SCHEMBL19967336 | 0.75 | TDP1 (0.52) | TDP1MAPTMDM2KMT2ACTDSP1 | |
| SCHEMBL19967190 | 0.75 | TDP1 (0.52) | TDP1MAPTMDM2KMT2ACTDSP1 | |
| SCHEMBL19967156 | 0.74 | FFAR4 (0.49) | TDP1MAPTGAASMN1; SMN2HRH3 | |
| SCHEMBL16116928 | 0.72 | TDP1 (0.58) | TDP1MAPTMDM2KMT2ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3509588-B1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | INTEGRAL HEALTH INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20210347768-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | VALO HEALTH, INC. | 2021-11-11 | — | — | US | disclosed |
| US-10865201-B2 | Bicyclic compounds useful as GPR120 modulators | VALO HEALTH, INC. (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190218208-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | VALO HEALTH, INC. | 2019-07-18 | — | — | US | disclosed |
| WO-2018049328-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | NUMERATE, INC. (US) | 2018-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865201-B2 | Bicyclic compounds useful as GPR120 modulators | GPR119, GPR180, GPR65 | TDP1 4753/4885MAPT 3630/4885GAA 2227/4885 |
| US-20190218208-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | TDP1 4753/4885MAPT 3630/4885GAA 2227/4885 |
| US-20210347768-A1 | BICYCLIC COMPOUNDS USEFUL AS GPR120 MODULATORS | GPR119, GPR180, GPR65 | TDP1 4753/4885MAPT 3630/4885GAA 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.