Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL1996751 | 1.00 | KMT2A (0.63) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL1897501 | 0.99 | KMT2A (0.61) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL1897497 | 0.99 | KMT2A (0.61) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL22635843 | 0.96 | KMT2A (0.58) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL8634349 | 0.94 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL8634348 | 0.94 | KMT2A (0.68) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL6390462 | 0.94 | KMT2A (0.55) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL28980603 | 0.93 | KMT2A (0.54) | KMT2AKDM4EMAPTLMNATSHR | |
| Dl-Tryptophan SCHEMBL634683 | 0.92 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR | |
| Tryptophan SCHEMBL78589 | 0.92 | KMT2A (0.74) | KMT2AKDM4EMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2337577-A1 | USE OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) AND PACAP ANALOGS AS ADJUNCTIVE TREATMENTS WITH ANTICANCER AGENTS | The Administrators of the Tulane Educational Fund (US) | 2011-06-29 | — | — | EP | disclosed |
| WO-2010036936-A2 | USE OF PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) AND PACAP ANALOGS AS ADJUNCTIVE TREATMENTS WITH ANTICANCER AGENTS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2010-04-01 | — | — | WO | disclosed |
| EP-1320594-A2 | EXBB-EXBD-TONB GENE CLUSTER OF PSEUDOMONAS PUTIDA DOT-T1E CONFERRING TOLERANCE TO AROMATIC COMPOUNDS AND RESISTANCE TO ANTIBIOTICS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002029034-A2 | EXBB-EXBD-TONB GENE CLUSTER OF PSEUDOMONAS PUTIDA DOT-T1E CONFERRING TOLERANCE TO AROMATIC COMPOUNDS AND RESISTANCE TO ANTIBIOTICS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-04-11 | — | — | WO | disclosed |