Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | BLM | P54132 | 2/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.68 |
| ▸ | MPO | P05164 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL8634348 | 1.00 | KMT2A (0.68) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL28059654 | 0.96 | KMT2A (0.74) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL28149832 | 0.96 | KMT2A (0.74) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL78589 | 0.96 | KMT2A (0.74) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL7943446 | 0.96 | KMT2A (0.74) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL634683 | 0.96 | KMT2A (0.74) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL1897497 | 0.95 | KMT2A (0.61) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL1897501 | 0.95 | KMT2A (0.61) | KMT2AKDM4EMAPTMEN1LMNA | |
| Tryptophan SCHEMBL11361648 | 0.95 | KMT2A (0.73) | KMT2AKDM4EMAPTMEN1LMNA | |
| Dl-Tryptophan SCHEMBL1996746 | 0.94 | KMT2A (0.63) | KMT2AKDM4EMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853667-A2 | BONE STIMULATING FACTOR | Gensci Regeneration Sciences Inc. (CA) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997012036-A2 | BONE STIMULATING FACTOR | GENSCI REGENERATION SCIENCES INC. (CA) | 1997-04-03 | — | — | WO | disclosed |