Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 20/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.70 |
| ▸ | DRD3 | P35462 | 2/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 18/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18114932 | 0.83 | OPRM1 (1.00) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18122729 | 0.83 | OPRM1 (1.00) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL19961503 | 0.80 | OPRM1 (0.75) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18114803 | 0.80 | OPRM1 (0.75) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18114814 | 0.80 | OPRM1 (1.00) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18114884 | 0.80 | OPRM1 (0.66) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18114886 | 0.79 | OPRM1 (1.00) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18122713 | 0.78 | OPRM1 (1.00) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18114854 | 0.78 | OPRM1 (0.67) | OPRM1OPRK1DRD2DRD3OPRD1 | |
| SCHEMBL18114874 | 0.77 | OPRM1 (0.69) | OPRM1OPRK1DRD2DRD3OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377698-B2 | Diphenethylamine derivatives which are inter alia useful as analgesics and method for their production | UNIVERSITY OF INNSBRUCK (AT) | 2019-08-13 | — | — | US | disclosed |
| US-20180072654-A1 | Diphenethylamine Derivatives Which Are Inter Alia Useful As Analgesics And Method For Their Production | Spetea, Mariana, Dr. (AT) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072654-A1 | Diphenethylamine Derivatives Which Are Inter Alia Useful As Analgesics And Method For Their Production | PNMT, OPRL1, OPRK1 | OPRM1 21/4885OPRK1 3/4885DRD2 79/4885 |
| US-10377698-B2 | Diphenethylamine derivatives which are inter alia useful as analgesics and method for their production | PNMT, OPRL1, OPRK1 | OPRM1 18/4885OPRK1 3/4885DRD2 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.