Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986366 | 0.80 | IDO1 (0.47) | CNR2CNR1P2RX7MAPTPOLB | |
| SCHEMBL1983582 | 0.78 | CNR2 (0.49) | CNR2CNR1P2RX7MAPTPOLB | |
| SCHEMBL2036426 | 0.73 | LMNA (0.54) | CNR2CNR1MAPTPOLBLMNA | |
| SCHEMBL2041249 | 0.71 | CHRM1 (0.46) | CNR2CNR1MAPTPOLBLMNA | |
| SCHEMBL12643105 | 0.71 | CNR2 (0.44) | CNR2CNR1P2RX7MAPTPOLB | |
| SCHEMBL1986391 | 0.71 | IDO1 (0.48) | CNR2CNR1LMNATPSAB1KDM4E | |
| SCHEMBL1985481 | 0.71 | ALDH1A1 (0.46) | CNR2CNR1MAPTTPSAB1ALDH1A1 | |
| SCHEMBL2036074 | 0.70 | P2RX7 (0.47) | CNR2CNR1P2RX7MAPTTPSAB1 | |
| SCHEMBL2033740 | 0.69 | P2RX7 (0.48) | CNR2CNR1P2RX7MAPTPOLB | |
| SCHEMBL6871072 | 0.69 | GRIN2B (0.38) | TP53P2RX7MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079103-A1 | SPIROPIPERIDINE BENZYLAMINES AS BETA-TRYPTASE INHIBITORS | SANOFI (FR) | 2011-06-30 | — | — | WO | disclosed |