Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.55 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 5/20 | 0.48 |
| ▸ | PRKACG | P22612 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23652014 | 0.89 | CYP3A4 (0.55) | CYP3A4TLR8GRM4MAOBMAOA | |
| SCHEMBL2329005 | 0.86 | CYP3A4 (0.55) | CYP3A4TLR8GRM4MAOBMAOA | |
| SCHEMBL24411225 | 0.86 | CYP3A4 (0.55) | CYP3A4TLR8GRM4MAOBMAOA | |
| SCHEMBL29214652 | 0.84 | CYP3A4 (0.52) | CYP3A4TLR8GRM4MAOBMAOA | |
| SCHEMBL28665368 | 0.83 | CYP3A4 (0.51) | CYP3A4GRM4MAOB | |
| SCHEMBL4465629 | 0.83 | FGFR2 (0.68) | PDGFRBPDGFRAMETFGFR2KIT | |
| SCHEMBL29214660 | 0.82 | CYP3A4 (0.51) | CYP3A4TLR8GRM4MAOBMAOA | |
| SCHEMBL19633698 | 0.82 | TUBB1 (0.57) | MET | |
| SCHEMBL311094 | 0.81 | CYP3A4 (0.58) | CYP3A4TLR8GRM4MAOBMAOA | |
| SCHEMBL6592222 | 0.81 | KDM1A (0.56) | PDGFRBPDGFRAFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018046460-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) | 2018-03-15 | — | — | WO | disclosed |