Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.57 |
| ▸ | GAK | O14976 | 7/20 | 0.55 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.55 |
| ▸ | COQ8A | Q8NI60 | 3/20 | 0.55 |
| ▸ | NLK | Q9UBE8 | 3/20 | 0.55 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633779 | 0.87 | TUBB1 (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19633749 | 0.87 | TUBB1 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19633697 | 0.86 | GAK (0.53) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19633713 | 0.83 | GAK (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19633706 | 0.83 | PDGFRA (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19968424 | 0.82 | CYP3A4 (0.57) | MET | |
| SCHEMBL19633688 | 0.80 | KDR (0.52) | EGFRMET | |
| SCHEMBL19633780 | 0.79 | GAK (0.71) | GAKRIPK2COQ8ANLKBMPR1B | |
| SCHEMBL19633760 | 0.79 | PDGFRA (0.48) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19633753 | 0.78 | GAK (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |