Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.51 |
| ▸ | CTSK | P43235 | 13/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSC | P53634 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21013700 | 0.88 | CTSK (0.52) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL20415718 | 0.87 | CTSC (0.58) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL2617400 | 0.87 | CTSS (0.65) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL2074401 | 0.87 | CTSS (0.51) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL2074403 | 0.87 | CTSS (0.51) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL2329795 | 0.86 | CTSS (0.65) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL2329798 | 0.86 | CTSS (0.65) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL28562312 | 0.86 | CTSK (0.50) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL18262402 | 0.86 | CTSS (0.53) | CTSSCTSKCTSBCTSLCTSC | |
| SCHEMBL28912771 | 0.86 | CTSL (0.53) | CTSSCTSKCTSBCTSLCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047139-A1 | COMPOUNDS AS MODULATORS OF TIGIT SIGNALLING PATHWAY | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-15 | — | — | WO | disclosed |