Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21791708 | 0.89 | TAAR1 (0.70) | TAAR1SLC6A4SLC6A2SLC6A3GAA | |
| Machilin A SCHEMBL31237868 | 0.85 | TAAR1 (0.74) | TAAR1SLC6A4SLC6A2SLC6A3GAA | |
| Machilin A SCHEMBL30678762 | 0.85 | TAAR1 (0.74) | TAAR1SLC6A4SLC6A2SLC6A3GAA | |
| Machilin A SCHEMBL10343221 | 0.85 | TAAR1 (0.74) | TAAR1SLC6A4SLC6A2SLC6A3GAA | |
| SCHEMBL5018909 | 0.85 | TAAR1 (0.59) | TAAR1SLC6A4SLC6A2SLC6A3GAA | |
| SCHEMBL3841679 | 0.82 | TAAR1 (0.81) | TAAR1SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL98038 | 0.82 | TAAR1 (0.56) | TAAR1SLC6A4SLC6A2SLC6A3GAA | |
| SCHEMBL22885190 | 0.82 | TAAR1 (0.81) | TAAR1SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL14199081 | 0.82 | TAAR1 (0.56) | TAAR1SLC6A4SLC6A2SLC6A3GAA | |
| Hydrochloric Acid SCHEMBL4685567 | 0.81 | TAAR1 (0.55) | TAAR1SLC6A4SLC6A2SLC6A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072677-A1 | Peptidomimetics and Methods of Using the Same | OPRM1, OPRL1, OPRD1 | TAAR1 174/4885SLC6A4 1406/4885SLC6A2 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.