SCHEMBL1996979

SCHEMBL1996979

ClCN(CCl)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 4/20 0.50
CNR2 P34972 1/20 0.47
AOC3 Q16853 1/20 0.46
NPC1 O15118 1/20 0.44
GLA P06280 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
PAX8 Q06710 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TRPA1 O75762 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
CA2 P00918 1/20 0.41
OPRM1 P35372 2/20 0.41
OPRD1 P41143 2/20 0.41
OPRK1 P41145 2/20 0.41
MAPK1 P28482 1/20 0.41
CALM1 P0DP23 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31327119 0.97 ALDH1A1 (0.48) ALDH1A1TSHRCNR2AOC3NPC1
SCHEMBL2795989 0.86 OPRM1 (0.44) ALDH1A1TSHRCNR2AOC3GLA
SCHEMBL134524 0.83 TSHR (0.60) ALDH1A1TSHRCNR2AOC3TRPA1
SCHEMBL373667 0.82 OPRM1 (0.48) ALDH1A1TSHRCNR2AOC3GLA
Chloromethane SCHEMBL27571631 0.81 CNR2 (0.59) ALDH1A1TSHRCNR2AOC3NPC1
Fluoride SCHEMBL633879 0.80 CNR2 (0.58) ALDH1A1TSHRCNR2AOC3TRPA1
Bromide SCHEMBL11212819 0.80 CNR2 (0.58) ALDH1A1TSHRCNR2AOC3TRPA1
Hydrochloric Acid SCHEMBL2137949 0.80 CNR2 (0.58) ALDH1A1TSHRCNR2AOC3SMN1; SMN2
Ammonia Solution, Strong SCHEMBL1348044 0.80 CNR2 (0.58) ALDH1A1TSHRCNR2AOC3TRPA1
SCHEMBL12049793 0.80 CNR2 (0.64) ALDH1A1TSHRCNR2AOC3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960305-B2 a mixture of a phosphazenium compound such as tetrakis[tris(dimethylamino)phosphoranylideneamino]phosphonium chloride, transition metal halides and an organic halogen compound as an activator, used for addition homo/copolymerization; living polymers MITSUI CHEMICALS, INC. (JP) 2011-06-14 US disclosed
US-20080177014-A1 Polymerization Catalyst Composition and Process for Production of Polymer MITSUI CHEMICALS, INC. (JP) 2008-07-24 US disclosed
EP-1857471-A1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER Mitsui Chemicals, Inc. (JP) 2007-11-21 EP disclosed