Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 9/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17170645 | 0.87 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL17885854 | 0.87 | ALDH1A1 (0.70) | ALDH1A1TSHRLMNAHTTCNR2 | |
| SCHEMBL17885856 | 0.86 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL12194245 | 0.84 | ALDH1A1 (0.75) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL17321387 | 0.84 | ALDH1A1 (0.74) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL17885845 | 0.82 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL5851294 | 0.80 | HTT (0.75) | ALDH1A1TSHRLMNAHTTL3MBTL1 | |
| SCHEMBL17170588 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL17321416 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 | |
| SCHEMBL17170606 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | TAKEDA CALIFORNIA, INC. | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072758-A1 | 5HT3 RECEPTOR ANTAGONISTS | HTR3A, HTR3B, HTR5A | ALDH1A1 1516/4885TSHR 289/4885LMNA 3514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.