Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131139 | 0.80 | NPC1 (0.37) | CTSLCTSSP4HTM | |
| SCHEMBL10170660 | 0.77 | ADRB2 (0.36) | P4HTM | |
| SCHEMBL21503684 | 0.72 | GABRA1 (0.37) | ESR1ESR2P4HTM | |
| SCHEMBL16672191 | 0.72 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL22296706 | 0.71 | BTK (0.34) | — | |
| SCHEMBL30175346 | 0.69 | HRH1 (0.39) | — | |
| SCHEMBL6468851 | 0.68 | KMT2A (0.41) | ESR1ESR2P4HTM | |
| SCHEMBL6469092 | 0.68 | KMT2A (0.41) | ESR1ESR2P4HTM | |
| SCHEMBL807532 | 0.66 | CCR1 (0.46) | P4HTM | |
| SCHEMBL13787913 | 0.66 | SMN1; SMN2 (0.38) | CTSLCTSSP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048761-A1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2018-03-15 | — | — | WO | disclosed |