Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.49 |
| ▸ | GRK6 | P43250 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19970831 | 0.87 | PSEN1 (0.55) | PARP1PTGDR2CYP2C9NPBWR1HPSE | |
| SCHEMBL19970875 | 0.86 | NPBWR1 (0.50) | PIN1PARP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7468723 | 0.84 | PPARG (0.58) | PTGDR2HPSEPPARGPIM1PIM3 | |
| SCHEMBL15245203 | 0.84 | NPBWR1 (0.57) | PTGDR2NPBWR1DGAT1KCNH2RXRA | |
| Hydrochloric Acid SCHEMBL7231022 | 0.83 | PPARG (0.57) | PTGDR2HPSEPPARGPIM1PIM3 | |
| SCHEMBL19970879 | 0.78 | KDM4E (0.58) | PPARGKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL3198870 | 0.77 | MEN1 (0.57) | PIN1PARP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22955338 | 0.77 | CYP3A4 (0.55) | PIN1PARP1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19970876 | 0.76 | NPBWR1 (0.60) | PIN1PARP1PTGDR2CYP1A2CYP3A4 | |
| SCHEMBL21705326 | 0.76 | NPBWR1 (0.67) | PARP1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292350-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | UNIVERSITE D'ORLEANS (FR) | 2021-09-23 | — | — | US | disclosed |
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292350-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | FIP1L1, ZC3HAV1, MAVS | PIN1 1946/4885PARP1 447/4885PTGDR2 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.