Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15245203 | 0.92 | NPBWR1 (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19970826 | 0.87 | PIN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19970793 | 0.85 | NPBWR1 (0.56) | NPBWR1DGAT1KCNH2SOAT1CHEK2 | |
| SCHEMBL7468723 | 0.84 | PPARG (0.58) | PTGDR2HPSECHEK2 | |
| SCHEMBL3865284 | 0.84 | CHEK2 (0.54) | PTGDR2HPSECHEK2 | |
| Hydrochloric Acid SCHEMBL7231022 | 0.83 | PPARG (0.57) | PTGDR2HPSECHEK2 | |
| SCHEMBL15245140 | 0.79 | DGAT1 (0.67) | NPBWR1DGAT1KCNH2SOAT1TNKS | |
| SCHEMBL2089777 | 0.78 | NPBWR1 (0.55) | NPBWR1DGAT1KCNH2SOAT1CHEK2 | |
| SCHEMBL15245202 | 0.78 | DGAT1 (0.59) | NPBWR1DGAT1KCNH2RXRARXRB | |
| SCHEMBL15245156 | 0.77 | DGAT1 (0.45) | PTGDR2NPBWR1DGAT1KCNH2HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292350-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | UNIVERSITE D'ORLEANS (FR) | 2021-09-23 | — | — | US | disclosed |
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292350-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | FIP1L1, ZC3HAV1, MAVS | PSEN1 2693/4885PSEN2 3073/4885APH1B 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.