Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15804495 | 1.00 | IDO1 (0.43) | IDO1LTA4HHDAC3EP300KAT2B | |
| SCHEMBL950509 | 0.85 | IDO1 (0.46) | IDO1LTA4HMEN1HCRTR1KMT2A | |
| SCHEMBL15807803 | 0.85 | IDO1 (0.46) | IDO1LTA4HMEN1HCRTR1KMT2A | |
| SCHEMBL15802471 | 0.84 | KMT2A (0.46) | IDO1LTA4HHDAC3EP300KAT2B | |
| SCHEMBL20644869 | 0.83 | MEN1 (0.41) | IDO1MEN1HCRTR1KMT2ASLC2A1 | |
| Bromide SCHEMBL19971055 | 0.82 | KMT2A (0.44) | IDO1LTA4HHDAC3EP300KAT2B | |
| Bromide SCHEMBL19971054 | 0.82 | KMT2A (0.44) | IDO1LTA4HHDAC3EP300KAT2B | |
| SCHEMBL19983512 | 0.82 | MEN1 (0.41) | IDO1EP300MEN1HCRTR1KMT2A | |
| SCHEMBL15802533 | 0.81 | IDO1 (0.40) | IDO1HDAC3EP300KAT2BKAT8 | |
| SCHEMBL9016080 | 0.80 | MEN1 (0.57) | MEN1HCRTR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931712-B1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | PARION SCIENCES INC (US) | 2018-03-21 | — | — | EP | disclosed |