Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 5/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644869 | 0.88 | MEN1 (0.41) | MEN1KMT2AHCRTR1CDC25BATM | |
| SCHEMBL19971042 | 0.82 | IDO1 (0.43) | MEN1KMT2AHCRTR1IDO1EP300 | |
| SCHEMBL15804495 | 0.82 | IDO1 (0.43) | MEN1KMT2AHCRTR1IDO1EP300 | |
| SCHEMBL15804490 | 0.81 | CTSK (0.46) | — | |
| SCHEMBL19971040 | 0.81 | CTSK (0.46) | — | |
| SCHEMBL15804492 | 0.74 | IDO1 (0.37) | CDC25BIDO1EP300 | |
| SCHEMBL15807803 | 0.73 | IDO1 (0.46) | MEN1KMT2AHCRTR1IDO1 | |
| SCHEMBL950509 | 0.73 | IDO1 (0.46) | MEN1KMT2AHCRTR1IDO1 | |
| SCHEMBL5763376 | 0.72 | NR3C1 (0.42) | MEN1KMT2AHCRTR1IDO1 | |
| SCHEMBL2435255 | 0.71 | CYP4F2 (0.63) | CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931712-B1 | 3,5-DIAMINO-6-CHLORO-N-(N-(4-PHENYLBUTYL)CARBAMIMIDOYL) PYRAZINE-2- CARBOXAMIDE COMPOUNDS | PARION SCIENCES INC (US) | 2018-03-21 | — | — | EP | disclosed |