Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28421670 | 0.83 | CA2 (0.33) | CA2CA1ALDH1A1TDP1TSHR | |
| SCHEMBL6983852 | 0.75 | SIRT2 (0.33) | CA2CA1LMNACA12CA3 | |
| Formamide SCHEMBL28230408 | 0.74 | ALDH1A1 (0.35) | CA2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL28692921 | 0.73 | ALDH1A1 (0.34) | ALDH1A1TDP1TSHRCYP3A4CYP2D6 | |
| SCHEMBL11131328 | 0.71 | CA2 (0.41) | CA2CA1ALDH1A1TDP1TSHR | |
| SCHEMBL6060679 | 0.67 | SIRT2 (0.38) | MEN1KMT2A | |
| SCHEMBL16909338 | 0.67 | CA2 (0.33) | CA2ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL3360175 | 0.66 | CA2 (0.42) | CA2CA1ALDH1A1TDP1TSHR | |
| SCHEMBL10523972 | 0.65 | CA2 (0.44) | CA2CA1ALDH1A1TDP1TSHR | |
| SCHEMBL30538382 | 0.65 | CA2 (0.44) | CA2CA1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111133018-B | Activators for promoted adhesion build | SIKA技术股份公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-108368233-B | Two-component polyurethane composition | SIKA技术股份公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-107428941-B | Amidino group-containing catalyst | SIKA技术股份公司 | 2020-11-24 | — | — | CN | disclosed |
| EP-3688052-A1 | ACTIVATOR FOR ACCELERATED ADHESION DEVELOPMENT | Sika Technology AG (CH) | 2020-08-05 | — | — | EP | disclosed |
| CN-107735438-B | Guanidino-containing catalysts | SIKA技术股份公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-111133018-A | Activators for promoted adhesion build | SIKA技术股份公司 | 2020-05-08 | — | — | CN | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |