Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971298 | 0.95 | EPHX2 (0.44) | EPHX2BBOX1PLA2G2APLA2G4AENPP2 | |
| SCHEMBL19971333 | 0.90 | BBOX1 (0.41) | EPHX2BBOX1SMN1; SMN2RXFP1 | |
| SCHEMBL19971176 | 0.88 | BBOX1 (0.38) | EPHX2BBOX1 | |
| SCHEMBL35104 | 0.85 | BBOX1 (0.47) | EPHX2BBOX1 | |
| SCHEMBL19220241 | 0.84 | EPHX2 (0.44) | EPHX2PLA2G2ACPT2CPT1ACPT1B | |
| SCHEMBL19971214 | 0.82 | BBOX1 (0.38) | EPHX2BBOX1ENPP2 | |
| SCHEMBL21545054 | 0.82 | BBOX1 (0.45) | EPHX2BBOX1 | |
| SCHEMBL19971257 | 0.81 | ZDHHC20 (0.53) | EPHX2BBOX1SMN1; SMN2RXFP1EPHX1 | |
| Lithium Ion SCHEMBL23607545 | 0.81 | EPHX2 (0.40) | EPHX2BBOX1PLA2G2APLA2G4ASMN1; SMN2 | |
| SCHEMBL18139610 | 0.81 | EPHX2 (0.40) | EPHX2BBOX1PLA2G2APLA2G4ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11530286-B2 | Sulfobetaine-based protein aggregation inhibitor for use in preventing aggregation of a protein | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2022-12-20 | — | — | US | disclosed |
| US-10995160-B2 | Protein aggregation inhibitor | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2021-05-04 | — | — | US | disclosed |
| US-20200332044-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2020-10-22 | — | — | US | disclosed |
| US-20190161563-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2019-05-30 | — | — | US | disclosed |
| US-20180118859-A1 | PROTEIN AGGREGATION INHIBITOR | OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) | 2018-05-03 | — | — | US | disclosed |
| EP-3296314-A1 | PROTEIN AGGREGATION INHIBITOR | Osaka Organic Chemical Industry Ltd. (JP) | 2018-03-21 | — | — | EP | disclosed |