SCHEMBL35104

SCHEMBL35104

C=C(C)C(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 3/20 0.47
EPHX2 P34913 1/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
GRK2 P25098 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
CBLB Q13191 5/20 0.34
ATM Q13315 1/20 0.33
APAF1 O14727 1/20 0.31
DNMT1 P26358 1/20 0.31
PTPN7 P35236 1/20 0.31
RECQL P46063 1/20 0.31
BLM P54132 1/20 0.31
PPP1CA P62136 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
PTPN22 Q9Y2R2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21545054 0.97 BBOX1 (0.45) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL16799339 0.96 BBOX1 (0.46) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL717860 0.96 BBOX1 (0.42) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL16799294 0.94 BBOX1 (0.45) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL18151769 0.94 BBOX1 (0.45) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL16799559 0.94 BBOX1 (0.41) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL18151216 0.94 BBOX1 (0.41) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL18151860 0.94 BBOX1 (0.41) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL18151638 0.94 BBOX1 (0.41) BBOX1EPHX2KMT2APOLBGRK2
SCHEMBL18151520 0.94 BBOX1 (0.45) BBOX1EPHX2KMT2APOLBGRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
WO-2025260202-A1 AIR PRINTING OF HYDROGELS ALLARTA LIFE SCIENCE INC. (CA) 2025-12-26 WO claimed
WO-2025260203-A1 CLICK CHEMISTRY POLYMER HYDROGELS ALLARTA LIFE SCIENCE INC. (CA) 2025-12-26 WO claimed
WO-2025260204-A1 CROSSLINKED HYDROGELS WITH CONTROLLED PERMEABILITY ALLARTA LIFE SCIENCE INC. (CA) 2025-12-26 WO claimed
US-20250263512-A1 POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE JOHNSON & JOHNSON VISION CARE (US) 2025-08-21 US claimed
WO-2025065051-A1 PLASMA-MEDIATED POLYMER GRAFTING METHODOLOGY THE UNIVERSITY OF SYDNEY (AU) 2025-04-03 WO claimed
EP-4520795-A1 ANTIFOULING MEMBER, MEMBER FOR IN-VITRO DIAGNOSTIC APPARATUS, AND METHOD OF PRODUCING ANTIFOULING MEMBER CANON KABUSHIKI KAISHA (JP) 2025-03-12 EP claimed
US-12247169-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2025-03-11 US claimed
US-20250075095-A1 ANTIFOULING MEMBER, MEMBER FOR IN-VITRO DIAGNOSTIC APPARATUS, AND METHOD OF PRODUCING ANTIFOULING MEMBER CANON KABUSHIKI KAISHA (JP) 2025-03-06 US claimed
EP-4514597-A1 METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
US-9125808-B2 Ionic silicone hydrogels JOHNSON & JOHNSON VISION CARE, INC. (US) 2015-09-08 US claimed
EP-2855544-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME Johnson & Johnson Vision Care Inc. (US) 2015-04-08 EP claimed
CN-104334596-A Polymer and nanogel materials and methods of making and using the same JOHNSON & JOHNSON VISION CARE 2015-02-04 CN claimed
US-20150011693-A1 Dispersed phase polymerization of halogenated vinyl monomers in the presence of live reactive stabilizers RHODIA OPERATIONS (FR) 2015-01-08 US claimed
EP-2794727-A1 IONIC SILICONE HYDROGELS Johnson & Johnson Vision Care Inc. (US) 2014-10-29 EP claimed
WO-2013176886-A2 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 WO claimed
US-20130317131-A1 POLYMERS AND NANOGEL MATERIALS AND METHODS FOR MAKING AND USING THE SAME JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-11-28 US claimed
US-20130217620-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-08-22 US claimed
US-20130168617-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-07-04 US claimed
WO-2013096604-A1 IONIC SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. (US) 2013-06-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130217620-A1 IONIC SILICONE HYDROGELS HACD2, IGFBP2, IGFBP6 BBOX1 3768/4885EPHX2 1731/4885KMT2A 2197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.