Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16626632 | 0.89 | RORC (0.49) | RORCPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL16619315 | 0.88 | RORC (0.49) | RORCPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28068082 | 0.88 | RORC (0.49) | RORCPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16618918 | 0.85 | RORC (0.51) | RORCPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16626638 | 0.82 | RORC (0.47) | RORCPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19971426 | 0.81 | RORC (0.45) | RORCBRD4 | |
| SCHEMBL17971568 | 0.74 | METAP2 (0.41) | RORCPDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL16618831 | 0.73 | METAP2 (0.41) | RORCMETAP2SCN9A | |
| SCHEMBL17971573 | 0.72 | RORC (0.51) | RORCBRD4 | |
| Hydrochloric Acid SCHEMBL16619011 | 0.72 | RORC (0.50) | RORCBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |